Coronary Flow Reserve on Cardiac PET
| Purpose | Automate measurement of myocardial blood flow and coronary flow reserve (CFR) on PET |
| Tag(s) |
|
| Panel | Cardiac |
| Define-AI ID | 18040005 |
| Originator | Dave Wymer |
| Panel Chair | Carlo De Cecco |
| Panel Reviewers | Cardiac Panel |
| License | |
| Status | Published |
Clinical Implementation
Value Proposition
Coronary flow reserve (CFR) using Rb-82 PET predicts major adverse cardiac events (MACE) independent of perfusion summed stress score parameters. Assessment of quantified coronary flow reserve could improve risk stratification in patients evaluated for ischemia.Narrative(s)
All patients receiving cardiac PET should have their coronary flow measured with calculated CFR, which may then be automatically populated into the radiology report or a report supplement.Workflow Description
A patient receives rest/stress protocol cardiac PET/CT using pharmacologic stress. Image sets are obtained along with 10-minute list mode acquisition. Automatic reorientation of the images to the American College of Cardiology and American Heart Association standards and automatic extraction of myocardial and cardiac cavity time-activity curves is performed. Flow quantification uses 1-tissue compartment model extraction with decay correction.Considerations for Dataset Development
Procedures(s): Dynamic acquisition Cardiac PET
View(s): Standard orthogonal Cardiac PET image set
Sex at Birth: {Male, Female}
Age: [0,90]
Body Surface Area: varied
Comorbidities: {Congenital heart disease, ventricular septal defects}
Interventions: {Congenital heart disease repair, ischemic heart disease repair}
Contrast Material: Rubidium-82 chloride
Technical Specifications
Inputs
DICOM Study
| Procedure | Dynamic acquisition Cardiac PET |
| Views | Standard orthogonal cardiac PET image set |
| Data Type | DICOM |
| Modality | PET |
| Body Region | Chest |
| Anatomic Focus | Heart |
| Pharmaceutical | Rubidium-82 chloride |
Primary Outputs
Myocardial Blood Flow
| RadElement ID | |
| Definition | Measure myocardial blood flow at rest and stress in each coronary artery distribution |
| Data Type | Numeric |
| Value Set |
|
| Units | Cc/gm/min |
Seventeen Segment Coronary Flow Reserves
| RadElement ID | |
| Definition | Calculate coronary flow reserves from myocardial blood flow for each of the AHA segments |
| Data Type | Numeric |
| Value Set |
|
| Units | Cc/gm/min |
Related Datasets
No known related public datasets at this time, please alert us if you know of any.